On Tuesday, the team behind the plan to return the animal -like animals to Tandra announced the creation of what is called woolen mice, which reminds us of the long fur with the Sufi mammoth. Long fur was created through the simultaneous liberation of seven genes, all with a connection known for the growth of hair, color and/or texture.
But do not think that this is a kind of mammogate hybrid. Most genetic changes were first identified in mice, not mammoths. Therefore, the focus is on the fact that the team can make simultaneous liberation for multiple genes-something they will need to do to get a large number of mammoth-like changes in the elephant’s genome.
Of mice and mammoths
The team at COLOSSAL BIOSCINCES has started a number of cancellation projects, including DOOD and Thylacine, but its main project is mammoth. In all of these cases, the plan is to take stem cells of unworthy -related species, and amend a series of changes based on the genotations corresponding to the deceased species. In the case of mammoth, this means elephant.
But the elephant raises a large number of challenges, as it admits the draft paper that describes new mice. “The period of pregnancy for 22 months of elephants and the reproductive time schedule makes the rapid experimental evaluation impractical,” researchers admit. “Moreover, the moral considerations related to the experimental manipulation of elephants, the endangered species with complex social structures and high cognitive capabilities require alternative methods of functional test.”
Therefore, they turned into a type used for genetic experiences for more than a century: mouse. We can do all kinds of genetic manipulation in mice and we have ways to use embryonic stem cells to get these manipulations to a new generation of mice.
For test purposes, the mouse also has a very important feature: it is easy to determine the mutations that change their fur. Throughout the excessive century we used to use mice to search, people noticed and noticed a large and varied collection of mutations that affect the fur, change their color, texture, and length. In many of these cases, the changes in the DNA were identified that cause these changes.