Photography of the thought catalog on non -earthquakes
The researchers tracked the brain’s changes in an unprecedented study of 1000 people
short
- People who used cannabis appear more than 1000 times a decrease in brain activity during memory tasks, even after a long period of stopping use
- The effects were more evident in the brain areas responsible for the working memory
- While the study found effects on memory function, other mental tasks such as emotional therapy, language and logical thinking were not greatly affected by hemp heard.
Aurora, Colorado – Do you think the effects of hemp worn as soon as you decide to quit good? Think again. New research indicates that the use of heavy marijuana can affect your mind memory functions after a long period of your last use. This result comes from one of the largest studies that have ever conducted on how cannabis affects the function of the brain.
Against the background of the codification of cannabis and the high effectiveness of marijuana products, researchers from the National Institute for alcohol and alcoholism, the College of Medicine at the University of Colorado, and the University of Toronto cooperated to conduct the largest study of its kind that examines how both examined both the use of modern and long -term cannabis affecting the brain function. Their results, published in Jama open networkHe suggested that using heavy hemp may have permanent effects on cognitive therapy, even after someone stops using the drug.
“With the continued use of cannabis in the world, the study of its effects on human health has become increasingly important. By doing this, we can provide a good understanding of all the benefits and risks of the use of cannabis, enabling people to make enlightened decisions and understand the potential consequences completely.” Radiology at the College of Medicine at the University of Colorado, in a statement.
The research team looked at the brain scanning of 1003 young men from the age of 22 and 36 years. They found that people who used cannabis greatly throughout their lives showed less activity in the brain during memory tasks compared to those who rarely use marijuana or have never been used. This difference was more clear in the brain areas that help us to pay attention, make decisions, and to store information temporarily.
The working memory is similar to a mental sticky note – it helps you remember the phone number for a long time enough to order it. We use this type of memory countless times every day, from following a conversation to solving problems or mentioning trends.
The researchers divided the participants into three groups based on the use of hemp for lifetime: heavy users (more than 1000 times), moderate users (10-999 times), and non-users (less than 10 times). Among everyone who studied, about 9 % of heavy users, 18 % of moderate users, were rarely used 73 % of cannabis. Heavy users were likely to be male, and they have low levels of income and education, and they show the use of the last cannabis in drug tests.
We applied the highest standards to our research, and set strict sills for statistical importance through all the seven cognitive functions tests. To reduce the risks of wrong positives, we used the correction of a false discovery rate (FDR). While some other tasks indicated a possible weak perception, the work of the working memory showed a statistically significant effect. “
Besides memory tasks, the study also looked at how to respond to the brains of participants during other mental challenges – things such as processing rewards, identifying emotions, language use, movement control, logical thinking, and understanding of others’ views. Interestingly, the use of heavy cannabis does not seem to greatly affect these other brain functions.
The team also found that people who recently used hashish (discovered through drug test) were worse in memory and movement tasks. However, these short -term effects were not strongly strong as long -term effects on memory.
The study revealed that there is an interesting difference between the sexes: men showed more clear effects than women when it comes to the activity of the movement associated with movement during the effect of hemp. This adds to increasing evidence that marijuana may affect men and women differently.
For anyone who uses hemp regularly, the research indicates that it may be useful to take rest periods before treating difficult tasks mentally. However, Gwen warned that stopping the use of hemp can also affect the axis capabilities. He said: “People need to be aware of their relationship with hashish because refraining from cold Türkiye can also disrupt their awareness.” “Heavy users may need to be more careful.”
Paper summary
methodology
Researchers have benefited from the data from the Human Connectome project, which collected the widespread imaging of brain and behavioral data between 2012-2015. Participants underwent functional magnetic resonance (FMRI) while performing seven different cognitive tasks. They also provided detailed information about the date of the use of hemp through uniform interviews and undergoing urine to detect modern use. The study controls possible confusing factors such as alcohol use, nicotine, education, income, and demographic variables.
results
Heavy lifeline users have shown a much lower stimulation of the brain during the working memory tasks compared to non -users, with a moderate effect (Cohen D = -0.28). This association remained even after the participants were excluded with the use of the last cannabis. The effect was more evident in the brain areas with high density of hemp receptors. The use of the last hemp was associated with a weak performance in the memory of work and the theory of mental tasks, although these effects did not escape the strict statistical corrections.
Restrictions
This research was transverse, not longitudinal, which means that it could not definitely prove that the use of hemp caused the noticeable differences in the brain function. The study focused on young adults, so the results may not be circulated on other age groups. Researchers lack detailed information about when heavy hemp used in the lives of the participants and they were unable to calculate the differences in the effectiveness of marijuana or consumption methods.
Discussion and fast food
These results indicate that the use of heavy cannabis may have permanent effects on the function of the brain, especially the working memory, even after taking off. This has important effects on public health messages about the use of marijuana. The research indicates that users may benefit from periods of refrain from sex before the tasks that require awareness, although the optimal period of these breaks is still unclear.
Finance and disclosure
This research has been supported by the National Institute of Mental Health, the National Institute for Drug Upper, and other National Institutes of Health through the human human project. Many authors have reported that various scholarships have been received, but no major conflict in interest has been revealed.
Publishing information
This study was published, entitled “The results of the brain function for the use of modern and lifelong cannabis”, in Jama open network On January 28, 2025. The research led Joshua to. Join, PhD, and his colleagues from multiple institutions including Colorado University, National Institute on alcohol and alcohol addiction, and the National Institute on Drug use.