Gene found to link obesity risk in labradors and humans

Dogs that are constantly displayed and vulnerable to excess weight shared a common part of biology with some people exposed to obesity.

This is what UK scientists have discovered – identifying a genetic source for many Labrador – and some people tend to excessive food.

The researchers have found that the changes in a specific gene, one of the basic building blocks of the biological symbol that produces a plan for how our bodies work changes the chemical signals that tell our brains that we have enough to eat.

Scientists say their results, It was published in the magazine ScienceIt reveals something “strong” about the biology of obesity.

“By studying dogs, we have sharpened in some interesting new biology here,” the main researcher Dr. Elianor Ravan of the Cambridge University Physiology, Development and Neurology Department.

She added that this discovery showed that “Slim Dogs are not morally superior – and the same applies to slim people.”

“If you have a great genetic risk of obesity, you are vulnerable to gaining weight unless you make a tremendous effort not to do so. Those who have low genetic risks do not have to work hard.”

This biological and human biological association came from researchers examining the genetics of 250 Labradors. Searching the team for pieces of genetic code that were common in excessive dogs.

Choose one gene in particular – called Dennd1B – which has been associated with a higher body mass in Labrador. When they looked at a library of genetic information from thousands of people, they discovered that the same gene was associated with a higher body mass in people as well.

Before this study of the genetics of Labrador, Dr. Ravan said: “No one is suspected of having any relationship with obesity.”

The gene interferes with the course of the brain signals that helps regulate our appetite.

“It changes the willingness to gain weight because it modifies a system involved in regulating our hunger and the amount of energy we burn.”

Results can help in the future development of new drug treatment. But scientists say that they reveal the difficulty of people – and dog owners – with this genetic willingness, should compensate for its effects.

Another member of the research team, Alice McLelalan, from the University of Cambridge, added that the results confirmed “the importance of the basic brain paths in controlling appetite and body weight.”

The discovery adds to a sophisticated image of these paths and biological driving forces behind excessive eating.

A group of weight loss medications, which include Ozmpic, targets some of these neighborhoods, and has exploded in popularity in recent years.

What we have identified here is a different path [from the one targeted by those drugs]Dr. Ravan explained.

“But everything talks about the same important thing of biology, which is that obesity is not related to a low will.

“It comes to the fact that some people are vulnerable to weight gain because they have a genetic risk, which increases food response and their appetite.

“This applies to both dogs and humans – they have a genetic engine to excessive eating.”