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Scientists in China have developed a potential vaccine to prevent plaque accumulation in the arteries that can lead to blood clots, stroke and heart attacks.
accumulation The fatty plate in the arteries, a condition known as atherosclerosis, is one of the main causes of death around the world. Mental sclerosis can ultimately lead to the arteries of inflammation from preventing blood flow and lead to a Stroke, vascular expansion, or heart attack.
Arteriosclerosis is an inflammatory disease, through the body’s fungal immunity that consists of natural barriers and enzymes as well as their adaptive systems that consist of antibodies.
Such arterial factors are treated, as soon as they are diagnosed by surveying, with surgical procedures such as blood vessels and the use of supports to prevent blood vessels from blockage.
Theoretical time ago is that vaccination can be used to treat or prevent it.
A new study published in the magazine Nature Communications A vaccine description may reduce the development of atherosclerosis in mice.
“The design of Nanovatch and pre -clinical data is a potential candidate for the preventive treatment for atherosclerosis,” said scientists at the Nanjing University of Science and Technology in China.
Previous studies have helped create a digital library of different types of proteins that protect against inflammation and enhance the immune response to the body to harden the arteries.
One of this protein is called P210. It has been found that it leads to an immune response against atherosclerosis, and this is what the new vaccine uses.
The vaccine holds the P210 antigen on the nanoparticles of the small iron oxide and connects an auxiliary material – used to enhance the immune response to the vaccine – to a different set of nanoparticles.
The study stated that the design of the “cocktail” of the vaccine reduces the development of plaque and the development of atherosclerosis in mice that nourish a high diet in the blood.
By helping the body succeeded in eating the antigen and the assistant, which then stimulated the stitching cells in the form of a star.
A series of changes from the vaccine ultimately led to the production of antibodies against P210.
“The results we find shows that the strategy of connecting Nanovachin has two effective parts against atherosclerosis,” the researchers write.
They hope to conduct more studies to understand the time that nanophachen protects from atherosclerosis.