By the time we notice the signs of cognitive decline due to aging, it is too late to effectively treat it. But take a look at the brain during the “critical window” between the ages of 40 and 59 Ticket in The facts of the National Academy of Sciences.
The study indicates that patients in that “window” are subject to functional magnetic resonance imaging (MRI) and Electricity (EEG). Photography tests can reveal these vital indicators associated with cognitive decline while continuing to provide enough time for effective treatment.
An insight into nervous degeneration
The expectation of the brain is difficult because it seems to follow a S -shaped curve instead of a straight line over time. In the study, an international team is separated by neuroscientists who bends and defines critical points. They used nervous imaging techniques on more than 19,300 people to determine these points.
The study shows that the first signs of a decline appear in about 44 years, as the nervous degeneration struck “the height of acceleration” at the age of 67, then up to 90 years.
“Understanding when and how the aging of the brain is accelerating, it gives us strategic time points for intervention,” Lilian R. Mujica BaroudiThe State University in New York, neurologist Stone Brook and author of the study, said in A. press release. “We have identified the critical middle window where the brain begins to experience low energy access, but before irreversible damage, mainly” bending “before” break “.
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Determining nervous stress
The researchers also identified a mechanism: nervous stress due to the lack of enough fuel. This tension occurs for middle -aged nerve cells. “They are struggling, but they are still applicable,” said Baroudi. “Therefore, providing alternative fuel during this critical window can help restore the job.”
Besides setting the aging path in the brain, the researchers also identified nervous insulin resistance as one of the main drivers. They have seen changes in genes that play a role in metabolism that precede the transformations in vascular indicators and infections.
Food for ideas
Good news? This gap between changes in brain metabolism and those permanent transformations that can weaken physically The brain represents an opportunity for treatment. They also identified “food” alternative to neurons that could ignore weakness.
They used this food, something called “ketone transmission”, in 101 participants in the study on different points of brain aging curve. The effects were striking, as the treatment was the most participant in the group of 40-59.
Instead of waiting to slip to the cognitive retreat curve, people may think Other strategies To combat cognitive decline. Citizen meals or ketone supplements may provide one path forward. If they are not sure of their mind, they may think of checking their head by photographing the brain.
Read more: Fighting the cognitive decline with these five activities
condition sources
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Before joining Discover, Paul Smaglik spent more than 20 years as a scientific journalist, specialized in American life sciences and international scientific job issues. He started his career in newspapers, but he turned into scientific journals. His work appeared in publications, including news of science, science, nature and scientific America.